Improving Individuals' Response to Drugs Based on Genetic Variation

Authors

  • Sabah attwan kazi Basra Education Directorate, Al-Hassan Al-Basri preporatory for Boys, University of Basra, College of Education for Pure Sciences, Department of Biology

Keywords:

Drug response, HLA, Genetic variation, CYP2C19, Improving Drug, Pharmacogenetics

Abstract

Pharmacogenetics is a quickly developing area that studies individual genetic differences to increase the effectiveness and reduce side effects. The detrimental effects of genetic associations—where certain genetic alterations result in undesired medication responses or decreased therapeutic efficacy—are the main focus of this study. A sample of 100 individuals was examined, taking into account certain genetic variants such as CYP2C19, HLA-B5701*, and SLCO1B1. The findings show a strong relationship between genetic variation and both the severity of side effects and the effectiveness of drugs. Research indicates that incorporating genetic profiling into treatment regimens can maximize therapeutic benefits and reduce side effects.

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Published

2025-03-11

How to Cite

kazi, S. attwan. (2025). Improving Individuals’ Response to Drugs Based on Genetic Variation. American Journal of Biology and Natural Sciences, 2(3), 102–111. Retrieved from https://biojournals.us/index.php/AJBNS/article/view/732