Modern Approaches to The Diagnosis and Treatment of Temporomandibular Joint Disorders
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Temporomandibular joint (TMJ) dysfunction is one of the most common pathologies resulting from disturbances in the function of the temporomandibular joint and its surrounding muscles, ranking third among dental diseases after caries and periodontal disease and affecting approximately 27–75% of the population worldwide. It is characterized by pain, restricted jaw movement, joint sounds, and impaired chewing function, and disproportionately affects women aged 20–40 due to hormonal and psychoemotional factors. This article reviews the etiology, clinical presentation, and modern methods of diagnosing and treating TMJ disorders, with the aim of informing preventive and therapeutic strategies. The review was prepared through a qualitative synthesis of scientific literature retrieved from the PubMed and Google Scholar databases, together with standard textbooks on maxillofacial surgery, focusing on studies addressing etiology, diagnostic imaging, artificial intelligence-assisted diagnostics, the DC/TMD diagnostic criteria, and conservative through minimally invasive treatment approaches. The findings indicate that TMJ disorders are polyetiological, involving predisposing, initiating, and perpetuating factors such as occlusal disturbances, bruxism, trauma, psychological stress, and estrogen-related effects. Diagnostic imaging (CBCT, CT, MRI) and artificial intelligence algorithms substantially improve diagnostic accuracy, while DC/TMD remains the most reliable standardized clinical protocol. Conservative treatment, including physiotherapy, occlusal splints, and pharmacotherapy, is recommended as first-line therapy, with minimally invasive options such as arthrocentesis and platelet-rich plasma therapy reserved for refractory cases. A comprehensive, individualized approach combining these modalities, together with psychological support, offers the most effective strategy for reducing pain and restoring joint function in patients with TMJ disorders.
[1] A. Y. Alqutaibi, M. S. Alhammadi, H. H. Hamadallah, et al., “Global prevalence of temporomandibular disorders: a systematic review and meta-analysis,” J. Oral Facial Pain Headache, vol. 39, no. 2, pp. 48–65, 2025.
[2] L. Dahlström and G. E. Carlsson, “Temporomandibular disorders and oral health-related quality of life: A systematic review,” Acta Odontol. Scand., vol. 68, no. 2, pp. 80–85, 2010.
[3] T. I. Suvinen, P. C. Reade, P. Kemppainen, M. Könönen, and S. F. Dworkin, “Review of aetiological concepts of temporomandibular pain disorders: towards a biopsychosocial model for integration of physical disorder factors with psychological and psychosocial illness impact factors,” Eur. J. Pain, vol. 9, no. 6, pp. 613–633, 2005.
[4] S. V. Tarasenko, Ed., Khirurgicheskaya Stomatologiya [Surgical Dentistry]. Moscow, Russia: GEOTAR-Media, 2021, (in Russian).
[5] A. Yu. Drobyshev and O. O. Yanushevich, Eds., Chelyustno-Litsevaya Khirurgiya [Maxillofacial Surgery]. Moscow, Russia: GEOTAR-Media, 2021, (in Russian).
[6] S. Sharma, D. S. Gupta, U. S. Pal, and S. K. Jurel, “Etiological factors of temporomandibular joint disorders,” Natl. J. Maxillofac. Surg., vol. 2, no. 2, pp. 116–119, 2011.
[7] A. M. Chisnoiu, A. M. Picos, S. Popa, P. D. Chisnoiu, L. Lascu, A. Picos, and R. Chisnoiu, “Factors involved in the etiology of temporomandibular disorders — a literature review,” Clujul Med., vol. 88, no. 4, pp. 473–478, 2015.
[8] Y. J. Shim, “Estrogen as a biological modulator in the temporomandibular joint: A narrative review,” J. Oral Med. Pain, vol. 51, no. 1, 2026.
[9] G. S. Dhabale and R. R. Bhowate, “Cone-beam computed tomography for temporomandibular joint imaging,” Cureus, vol. 14, no. 11, art. e31515, 2022.
[10] N. Jha, K.-s. Lee, and Y.-J. Kim, “Diagnosis of temporomandibular disorders using artificial intelligence technologies: A systematic review and meta-analysis,” PLoS ONE, vol. 17, no. 8, art. e0272715, 2022.
[11] S. Kar, G. Srivastava, N. Hirani, A. S. Dupare, S. Gupta, and S. Roy, “Artificial intelligence in the diagnosis of temporomandibular joint disorders using cone-beam computed tomography (CBCT),” Bioinformation, vol. 21, no. 8, 2025.
[12] E. Schiffman, R. Ohrbach, E. Truelove, et al., “Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group,” J. Oral Facial Pain Headache, vol. 28, no. 1, pp. 6–27, 2014.
[13] R. L. Gauer and M. J. Semidey, “Diagnosis and treatment of temporomandibular disorders,” Am. Fam. Physician, vol. 91, no. 6, pp. 378–386, 2015.
[14] E. A. Al-Moraissi, P. C. R. Conti, A. Alyahya, K. Alkebsi, A. Elsharkawy, and N. Christidis, “The hierarchy of different treatments for myogenous temporomandibular disorders: a systematic review and network meta-analysis of randomized clinical trials,” Oral Maxillofac. Surg., vol. 26, no. 4, pp. 519–533, 2022.
[15] H. Albagieh, I. Alomran, A. Binakresh, N. Alhatarisha, M. Almeteb, Y. Khalaf, A. Alqublan, and M. Alqahatany, “Occlusal splints — types and effectiveness in temporomandibular disorder management,” Saudi Dent. J., vol. 35, no. 1, pp. 70–79, 2023.
[16] J. Xu, H. Ren, S. Zhao, Q. Li, C. Li, G. Bao, and H. Kang, “Comparative effectiveness of hyaluronic acid, platelet-rich plasma, and platelet-rich fibrin in treating temporomandibular disorders: a systematic review and network meta-analysis,” Head Face Med., vol. 19, art. 39, 2023.
[17] F. Zotti, M. Albanese, L. F. Rodella, and P. F. Nocini, “Platelet-rich plasma in treatment of temporomandibular joint dysfunctions: Narrative review,” Int. J. Mol. Sci., vol. 20, no. 2, art. 277, 2019.
[18] A. Soni, “Arthrocentesis of temporomandibular joint — bridging the gap between non-surgical and surgical treatment,” Ann. Maxillofac. Surg., vol. 9, no. 1, pp. 158–167, 2019.

