The Efficacy of a Combination of Spirulina Fortified Chicken Breast Protein in Regulating Blood Sugar, Reducing Oxidative Stress, and Enhancing Pancreatic Function in Female Rats with Alloxan – Induced Diabetes
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This study aimed to highlight the importance of following a healthy diet – specifically one rich in protein and fiber – due to its significant health benefits , such as regulating blood sugar levels , reducing insulin resistance and oxidative stress caused by free radicals , and boosting immunity. This study utilized a reparation of Spirulina – fortified chicken breast – which had been thoroughly cooked , pressed, dried , and processed into a form suitable for mixing with the standard diet – to feed the animals for 40 days . The subjects were 48 female Wistar rats ,aged 13-14 months and weighing 128-186g .Diabetes was induced using alloxan (156 mg/kg) ,and the animals were divided into three groups of 16 each : Group A (healthy control ), Group B (diabetic control) , and Group C (diabetic group fed a chicken protein blend supplemented with Spirulina ). Upon completion of the experiment ,the results demonstrated the blends ability to regulate blood glucose levels, reduce insulin resistance ,and increase levels of glutathione and glutathione peroxidase .Additionally , it lowered malondialdehyde – a clear marker of oxidative stress and inflammation – while restoring the structural integrity of the pancreas (damaged by alloxan ) and reactivating beta-cell function.
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