Clinical Epidemiology of the Global Expansion of Klebsiella Pneumonia

Saja Sattar Jaber Ali; Moeaml Wahed motar Juma; Abdulkareem Abdullah Maakit Mohammed; Ridha Majhool Atya Dhiyab

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Saja Sattar Jaber Ali Al-Farabi University College Department Biology
Moeaml Wahed motar Juma Al-Qasiml Green Univetsity College of sciences Department Biology
Abdulkareem Abdullah Maakit Mohammed University of Babylon College of Science, Department of Biology
Ridha Majhool Atya Dhiyab University of Babylon College of Science, Department of Biology

Vol. 1 No. 10 (2024): American Journal of Biomedicine and Pharmacy

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December 20, 2024

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Klebsiella pneumoniae BSIs are associated with high mortality rates worldwide. The emergence of antibiotic-resistant K. pneumoniae complicates the management of infections caused by these bacteria. This study aimed to evaluate the epidemiology, resistance profiles, and clinical outcomes of K. pneumoniae BSIs. The infection rate was slightly higher in females (52%) than in males (48%). The ICU and ER had the highest prevalence of K. pneumoniae BSI. ICUs are considered factories that create, amplify, and disseminate antibiotic resistance [20, 21]. The high prevalence of antibiotic resistance in ICUs might be due to multiple infections, frequent application of antimicrobials, or the frequent use of invasive procedures. In our study, Klebsiella pneumoniae BSIs in patients admitted to the ICU were significantly associated with multiple risk factors including carbapenem resistance, mechanical ventilation, respiratory infection, multi-organ dysfunction, ischemic heart disease, and septic shock were significantly higher among ICU patients than non-ICU patients. In a recent study by Wang et al. (2023), age over 70 years, admission to ICU, and urinary tract infection were found to be the risk factors for Carbapenem-resistant and ESBL-KP-resistance.

Ali, S. S. J., Juma, M. W. motar, Mohammed, A. A. M., & Dhiyab, R. M. A. (2024). Clinical Epidemiology of the Global Expansion of Klebsiella Pneumonia. American Journal of Biomedicine and Pharmacy, 1(10), 16–25. Retrieved from https://biojournals.us/index.php/AJBP/article/view/380

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