The Importance of Oxidative Stress in the Development of Chronic Kidney Disease in the Context of Chronic Heart Failure
Keywords:
oxidative stress, chronic kidney disease, chronic heart failure, antioxidant system, superoxide dismutase.Abstract
The review article presents current research data on the important role of oxidative stress in the pathogenesis of chronic kidney disease against the background of chronic heart failure as well as modern approaches to eliminate the effects of exposure to active oxygen forms and/or preventing their excessive initiation. We described the markers of oxidative stress and the modern methods of determination of the free radical oxidation and antioxidant products in various tissues.
References
Арутюнов, Г.П. Патофизиологические процессы в почках у больных ХСН. Журнал сердечная недостаточность. 2008;9(5): 234-249.;
Sies, H. Oxidative stress: Oxidants and antioxidants. Exp. Physiol. 1997, 82, 291–295.
Hafstad, A.D.; Nabeebaccus, A.A.; Shah, A.M. Novel aspects of ROS signalling in heart failure. Basic Res. Cardiol. 2013, 108, 359.;Sirker, A.; Zhang, M.; Shah, A.M. NADPH oxidases in cardiovascular disease: Insights from in vivo models and clinical studies. Basic Res. Cardiol.2011, 106, 735–747.
Modlinger, P.S.; Wilcox, C.S.; Aslam, S. Nitric oxide, oxidative stress, and progression of chronic renal failure. WB Saunders. Semin. Nephrol. 2004, 24, 354–365.
Maack, C.; Böhm, M. Targeting mitochondrial oxidative stress in heart failure. Throttling the afterburner. J. Am. Coll. Cardiol. 2011, 58, 83–86.
Chen, L.; Knowlton, A.A. Mitochondrial dynamics in heart failure. Congest. Heart Fail 2010, 17, 257–261.
Beer, M.; Seyfarth, T.; Sandstede, J.; Landschütz, W.; Lipke, C.; Köstler, H.; von Kienlin, M.; Harre, K.; Hahn, D.; Neubauer, S. Absolute concentrations of high-energy phosphate metabolites in normal, hypertrophied, and failing human myocardium measured noninvasively with (31)P-SLOOP magnetic resonance spectroscopy. J. Am. Coll. Cardiol. 2002, 40, 1267–1274.;
Kato, T.; Niizuma, S.; Inuzuka, Y.; Kawashima, T.; Okuda, J.; Tamaki, Y.; Iwanaga, Y.; Narazaki, M.; Matsuda, T.; Soga, T.; et al. Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure. Circ. Heart Fail 2010, 3, 420–430.;
Nagase, M. Activation of the aldosterone/mineralocorticoid receptor system in chronic kidney disease and metabolic syndrome. Clin. Exp. Nephrol. 2010, 14, 303–314.
Zou, A.P.; Li, N.; Cowley, A.W. Production and actions of superoxide in the renal medulla. Hypertension 2001, 37, 547–553.;
López, B.; Salom, M.G.; Arregui, B.; Valero, F.; Fenoy, F.J. Role of superoxide in modulating the renal effects of angiotensin II. Hypertension 2003, 42, 1150–1156.;
Raij, L. Nitric oxide and cardiovascular and renal effects.Osteoarthr.Cartil.2008, 16, S21–S26.
Zelko IN, Mariani TJ, Folz RJ. Superoxide dismutase multigene family: acomparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD(SOD3) gene structures, evolution, and expression. Free Radic BiolMed. 2002;33:337–349.
Alcaino H, Greig D, Chiong M, Verdejo H, Miranda R, Concepcion R, Vukasovic JL, Diaz-Araya G, Mellado R, Garcia L, et al. Serum uric acidcorrelates with extracellular superoxide dismutase activity in patientswith chronic heart failure. Eur J Heart Fail. 2008;10:646–651.;
Rababa’h AM, Guillory AN, Mustafa R, Hijjawi T. Oxidative stress and cardiac remodeling: an updated edge. CurrCardiol Rev. 2018;14:53–59.;