Asthmatic Attacks against Specific Primary School Students in Baghdad, Iraq

Authors

  • Saad Abdul Kareem Mohammed Department of Pharmacy-AL-Rasheed University College, Baghdad/Iraq
  • Ali Saad Abdul Kareem Mohammed Al-Esraa University/ College of pharmacy, Baghdad/Iraq
  • Esraa Ghazy Jabbar Department of Pharmacy-AL-Rasheed University College, Baghdad/Iraq

Keywords:

Asthma, Primary school children, Alrusafa-Baghdad/Iraq

Abstract

Background: Certain stimuli can readily irritate the lungs and airways in children with asthma. Potential causes include, for instance, breathing in pollen or getting a cold or other respiratory illness. Play, sports, school, and sleep can all be disrupted by the irritating daily symptoms of childhood asthma [1]. For certain children, untreated asthma may result in potentially fatal episodes. Although it has distinct consequences, childhood asthma is not distinct from adult asthma. The illness is the main cause of hospital stays, emergency department (ED) visits, and absences from school. Asthma in children is unfortunately incurable, and symptoms may last into adulthood. Children can, however, control symptoms and safeguard their growing lungs with the right care [2].

Objective: This short study aims to identify certain risk factors that may increase the probability of developing asthma in some children under the age of 11 at Alrussafa-Baghdad.

Methods: This survey was conducted in Baghdad to determine the prevalence of asthma among primary school students aged 7 to 11, with an average age of 9 years. The study was conducted from October to December 2024 at Al-Ilwiyah Paediatric Teaching Hospital in Al-Rusafa, Baghdad. Sixty children were included, 30 with bronchial asthma and 30 without asthma, control groups were gathered using face-to-face questionnaires directed to the child’s parents following the clinical examination of children by the consultant paediatrician at the hospital's outpatient clinic.

Results: There was no significant difference (p-value > 0.05) in gender distribution between asthmatic and non-asthmatic teams, as measured by frequency percentage: male = (16, 53%) and female = (14, 47%). Males (18, 60%) and females (12, 40%) were non-asthmatic, respectively. In this study, the prevalence of bronchial asthma was 2.1% (p-value = 0.04), which is statistically significant (p < 0.05).

Conclusions: This Questionnaire indicated that crowding index, non-breastfeeding, family social status, mother’s education, family smoking history, family history of asthma, and food hypersensitivity reaction were all significant risk variables for illness severity (p-value = 0.001, p-value < 0.05).

References

Afrah G. Salih, Kassim J. Al-shamma, Mahir M. Hassan, Raed Y. Salman, et al. Treatment options of acute viral bronchiolitis in two Iraqi pediatric hospitals with a recent montelukast treatment option. AJPS. 2013;13(2):87-94. doi:10.32947/ajps.v13i2.206.

Ali L. Jassim, Kassim J. Al-shamma, Zaid M. Kadhum, et al. Comparing the clinical efficacy and safety of high doses of beclomethasone inhaler with medium doses of beclomethasone inhaler combined with oral aminophylline or montelukast tablets in persistent asthmatic Iraqi patients. AJPS. 2011;9(1):63-72. doi:10.32947/ajps.v9i1.272.

Freitas AS, Simoneti CS, Ferraz E, et al. Exposure to high endotoxin concentration increases wheezing prevalence among laboratory animal workers: a cross-sectional study. BMC Pubm Med. 2016 May 6;16(1):69. doi: 10.1186/s12890-016-0233-1.

Mersha TB, Qin K, Beck AF, et al. Genetic ancestry differences in pediatric asthma readmission are mediated by socioenvironmental factors. J Allergy Clin Immunol. 2021 Nov;148(5):1210-1218.e4. doi: 10.1016/j.jaci.2021.05.046.

Maciag MC, Phipatanakul W. Prevention of Asthma: Targets for Intervention. Chest. 2020 Sep;158(3):913-922. doi: 10.1016/j.chest.2020.04.011.

Ramette A, Spycher BD, Wang J, et al. Longitudinal Associations Between Respiratory Infections and Asthma in Young Children. Am J Epidemiol. 2018 Aug 1;187(8):1714-1720. doi: 10.1093/aje/kwy053.

Gent JF, Holford TR, Bracken MB, et al. Childhood asthma and household exposures to nitrogen dioxide and fine particles: a triple-crossover randomized intervention trial. J Asthma. 2023 Apr;60(4):744-753. doi: 10.1080/02770903.2022.2093219.

Lizzo JM, Goldin J, Cortes S. Pediatric Asthma. [Updated 2024 May 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551631/.

Omima Mohammed OMA, Majeed Mohamed Salih OA, Omer IIA, et al. Frequency of Severe Asthma and Its Clinical Phenotypes at the Asthma Clinic in One of the Largest Sudanese Tertiary Pediatric Hospitals: A Cross-Sectional Hospital-Outpatient-Based Study. J Asthma Allergy. 2024 Jul 22;17:693-702. doi: 10.2147/JAA.S450379.

Kato M, Miyamoto M, Takayanagi F, et al. Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation. J Immunol Res. 2023 Mar 9;2023:4075264. doi: 10.1155/2023/4075264.

Lizzo JM, Goldin J, Cortes S. Pediatric Asthma. [Updated 2024 May 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK551631/

Scadding GK, McDonald M, Backer V, et al. Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1-allergic asthma. Front Allergy. 2024 Jan 30;4:1291185. doi: 10.3389/falgy.2023.1291185.

Baker MG, McDonald A, Zhang J, et al. Infectious diseases attributable to household crowding in New Zealand: A systematic review and burden of disease estimate. Wellington: He Kainga Oranga/ Housing and Health Research Programme, University of Otago, 2013.

Gern JE. The Urban Environment and Childhood Asthma study. J Allergy Clin Immunol. 2010 Mar;125(3):545-9. doi: 10.1016/j.jaci.2010.01.037. [Cited 2024 Aug] Available from: doi: 10.1186/s12889-024-18716-2.

Kumar PH, Devgan A. The Association of Breastfeeding With Childhood Asthma: A Case-Control Study From India. Cureus. 2021 Nov 22;13(11):e19810. doi: 10.7759/cureus.19810. [Cited 2024 Jan] Available from: doi: 10.1038/s41591-023-02743-4. Epub 2024 Jan 9.

Dogaru CM, Nyffenegger D, Pescatore AM, et al. Breastfeeding and childhood asthma: systematic review and meta-analysis. Am J Epidemiol. 2014 May 15;179(10):1153-67. doi: 10.1093/aje/kwu072. [Cited 2024 Jul] Available from: doi: 10.3390/microorganisms12071471.

Howie PW, Forsyth JS, Ogston SA, et al. Protective effect of breast feeding against infection. BMJ. 1990 Jan 6;300(6716):11-6. doi: 10.1136/bmj.300.6716.11. [Cited 2024 May] Available from: doi: 10.1038/s41467-024-47955-5.

Wills-Karp M, Brandt D, Morrow AL. Understanding the origin of asthma and its relationship to breastfeeding. Adv Exp Med Biol. 2004;554:171-91. doi: 10.1007/978-1-4757-4242-8_16. [Cited 2023 Aug] Available from: doi: 10.3390/nu15153435.

Braveman P. Health disparities and health equity: concepts and measurement. Annu Rev Public Health. 2006;27:167-94. doi: 10.1146/annurev.publhealth.27.021405.102103. [Cited 2024 Aug] Available from: doi: 10.7759/cureus.68066. eCollection 2024 Aug.

Lai CK, Beasley R, Crane J, et al; International Study of Asthma and Allergies in Childhood Phase Three Study Group. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2009 Jun;64(6):476-83. doi: 10.1136/thx.2008.106609. Epub 2009 Feb 22. [Cited 2024 Oct] Available from: doi: 10.1007/s00431-024-05747-5. Online ahead of print.

Teixeira S, Zuberi A. Neighborhood Social and Environmental Factors and Asthma Among Children Living in Low-Income Neighborhoods: The Importance of Informal Social Control. Fam Community Health. 2018 Oct/Dec;41(4):214-224. doi: 10.1097/FCH.0000000000000202. [Cited 2024 Jun] Available from: doi: 10.1186/s41256-024-00361-2.

Nielsen KG, Bisgaard H. Hyperventilation with cold versus dry air in 2- to 5-year-old children with asthma. Am J Respir Crit Care Med. 2005 Feb 1;171(3):238-41. doi: 10.1164/rccm.200404-528OC. Epub 2004 Nov 12. [Cited 2022 Jun] Available from: doi: 10.3390/children9060920.

Largent J, Nickerson B, Cooper D, et al. Paediatric asthma hospital utilization varies by demographic factors and area socio-economic status. Public Health. 2012 Nov;126(11):928-36. doi: 10.1016/j.puhe.2012.04.011. [Cited 2023 Apr] Available from doi: 10.1016/j.waojou.2023.100764.

Braveman P. Health disparities and health equity: concepts and measurement. Annu Rev Public Health. 2006;27:167-94. doi: 10.1146/annurev.publhealth.27.021405.102103. [Cited 2024 Aug] Available from doi: 10.7759/cureus.68066.

Ogbu CE, Ogbu SC, Khadka D, et al. Childhood Asthma and Smoking: Moderating Effect of Preterm Status and Birth Weight. Cureus. 2021 Apr 17;13(4):e14536. doi: 10.7759/cureus.14536. [Cited 2024 Aug] Available from doi: 10.1186/s12889-024-18716-2.

Cheraghi M, Salvi S. Environmental tobacco smoke (ETS) and respiratory health in children. Eur J Pediatr. 2009 Aug;168(8):897-905. doi: 10.1007/s00431-009-0967-3. Epub 2009 Mar 20. [Cited 2023 Dec] Available from doi: 10.47176/mjiri.37.135.

London SJ, James Gauderman W, Avol E, et al. Family history and the risk of early-onset persistent, early-onset transient, and late-onset asthma. Epidemiology. 2001 Sep;12(5):577-83. doi: 10.1097/00001648-200109000-00019. [Cited 2024 Jan] Available from doi: 10.1186/s13148-023-01611-9.

Duffy DL. Genetic epidemiology of asthma. Epidemiol Rev. 1997;19(1):129-43. doi: 10.1093/oxfordjournals.epirev.a017935. [Cited 2022 Nov] Available from doi: 10.1038/s41598-022-21631-4.

Martinez FD, Wright AL, Taussig LM, et al. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med. 1995 Jan 19;332(3):133-8. doi: 10.1056/NEJM199501193320301. [Cited 2024 Oct] Available from doi: 10.1186/s12887-024-05101-6.

Martinez FD, Helms PJ. Types of asthma and wheezing. Eur Respir J Suppl. 1998 Jul;27:3s-8s. PMID: 9699776. [Cited 2022 Nov] Available from doi: 10.3390/s22218582.

Cookson WO, Moffatt MF. Asthma: an epidemic in the absence of infection? Science. 1997 Jan 3;275(5296):41-2. doi: 10.1126/science.275.5296.41. [Cited 2022 Feb] Available from doi: 10.3389/fimmu.2022.805770.

Holt PG, Macaubas C, Prescott SL, Sly PD. Primary sensitization to inhalant allergens. Am J Respir Crit Care Med. 2000 Sep;162(3 Pt 2):S91-4. doi: 10.1164/ajrccm.162.supplement_2.ras-7. [Cited 2007 Sep] Available from doi: 10.1111/j.1365-2222.2007.02775.x.

Morales E, Duffy D. Genetics and Gene-Environment Interactions in Childhood and Adult Onset Asthma. Front Pediatr. 2019 Dec 11;7:499. doi: 10.3389/fped.2019.00499. [Cited 2024 Jul] Available from doi: 10.21037/tp-24-117.

Dharmage SC, Lowe AJ, Matheson MC, et al. Atopic dermatitis and the atopic march revisited. Allergy. 2014 Jan;69(1):17-27. doi: 10.1111/all.12268. Epub 2013 Oct 14. [Cited 2024 Feb] Available from https://doi.org/10.3390/cells13050425.

Kusunoki T, Morimoto T, Nishikomori R, et al. Allergic status of schoolchildren with food allergy to eggs, milk or wheat in infancy. Pediatr Allergy Immunol. 2009 Nov;20(7):642-7. doi: 10.1111/j.1399-3038.2009.00856.x. Epub 2009 Aug 21. [Cited 2024 First Edition] Available from https://doi.org/10.1016/B978-0-323-96018-2.00157-7.

Caffarelli C, Garrubba M, Greco C, Mastrorilli C, et al. Asthma and Food Allergy in Children: Is There a Connection or Interaction? Front Pediatr. 2016 Apr 5;4:34. doi: 10.3389/fped.2016.00034. [Cited 2024 Oct] Available from https://doi.org/10.1016/j.clnesp.2024.07.010

Dilber DH, Ozceker D, Terzi O. Drug Allergy in Children: What is the Actual Frequency of Drug Allergies? Sisli Etfal Hastan Tip Bul. 2022 Dec 19;56(4):552-558. doi: 10.14744/SEMB.2022.65642.

Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Drug allergy: an updated practice parameter. Ann Allergy Asthma Immunol. 2010 Oct;105(4):259-273. doi: 10.1016/j.anai.2010.08.002. [Cited 2021 Apr] Available from https://doi.org/10.3390/cells10051033.

Pichler WJ. Delayed drug hypersensitivity reactions. Ann Intern Med. 2003 Oct 21;139(8):683-93. doi: 10.7326/0003-4819-139-8-200310210-00012. [Cited 2023 Oct] Available from https://doi.org/10.1111/all.15889.

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Published

2025-03-08

How to Cite

Mohammed , S. A. K., Mohammed , A. S. A. K., & Jabbar, E. G. (2025). Asthmatic Attacks against Specific Primary School Students in Baghdad, Iraq. American Journal of Biomedicine and Pharmacy, 2(3), 11–21. Retrieved from https://biojournals.us/index.php/AJBP/article/view/712

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