The Importance of Clotho Proteinin the Development of Chronic Kidney Disease in the Context of Chronic Heart Failure

Djuraeva Nozima Orifovna

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Djuraeva Nozima Orifovna Bukhara State Medical Institute, Uzbekistan, Bukhara

Vol. 2 No. 6 (2025): American Journal of Biomedicine and Pharmacy

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June 12, 2025

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The review article presents current research data on the importance of the Clotho proteinin the pathogenesis of chronic kidney disease in the context of chronic heart failure. The relationship of the Clotho protein with fibroblast growth factor–23 and its antioxidant properties is presented. It has been describedthat the α–clotho protein reduces the development of endothelial dysfunction and atherosclerosis by reducing oxidative stress and inflammation.

Djuraeva Nozima Orifovna. (2025). The Importance of Clotho Proteinin the Development of Chronic Kidney Disease in the Context of Chronic Heart Failure. American Journal of Biomedicine and Pharmacy, 2(6), 34–38. Retrieved from https://biojournals.us/index.php/AJBP/article/view/1091

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