Synthesis, Diagnosis And Evaluation Of The Antibacterial Activity Of New Oxazepane Derivatives
Keywords:
Heterocyclic, Oxazapane, Biological ActivityAbstract
The pharmaceutical molecule was prepared, tested, and compared to the antibiotic amoxicillin in terms of efficacy against two different strains of Gram-positive bacteria (Staphylococcus aureus and Gram-negative Escherichia coli). The investigated chemical was created by reacting succinic anhydride, which was obtained from the Schiff base of benzothiazole as a nucleus, with oxazole, which was obtained from a seven-membered ring by sublimation in the presence of dry benzene as a solvent. To confirm the correctness and validity of the results, spectroscopic techniques like proton nuclear magnetic resonance spectroscopy and infrared spectroscopy are employed in addition to physical measurements like product ratio and melting point.