Synthesis, Diagnosis And Evaluation Of The Antibacterial Activity Of New Oxazepane Derivatives

Authors

  • Farah M. Muhammad Tikrit University/College of Education for Pure Sciences/Department of Chemistry

Keywords:

Heterocyclic, Oxazapane, Biological Activity

Abstract

The pharmaceutical molecule was prepared, tested, and compared to the antibiotic amoxicillin in terms of efficacy against two different strains of Gram-positive bacteria (Staphylococcus aureus and Gram-negative Escherichia coli). The investigated chemical was created by reacting succinic anhydride, which was obtained from the Schiff base of benzothiazole as a nucleus, with oxazole, which was obtained from a seven-membered ring by sublimation in the presence of dry benzene as a solvent. To confirm the correctness and validity of the results, spectroscopic techniques like proton nuclear magnetic resonance spectroscopy and infrared spectroscopy are employed in addition to physical measurements like product ratio and melting point.

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Published

2024-09-05

How to Cite

Farah M. Muhammad. (2024). Synthesis, Diagnosis And Evaluation Of The Antibacterial Activity Of New Oxazepane Derivatives. American Journal of Bioscience and Clinical Integrity, 1(9), 9–18. Retrieved from https://biojournals.us/index.php/AJBCI/article/view/97

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